What is convalescent plasma?

Convalescent plasma (plasma) is yellow liquid portion of the blood which contain antibodies to fight against the novel coronavirus (SARS-COV2). It is obtained from blood donated by fully recovered COVID-19 patients, who are asymptomatic. The blood is processed by blood bank to extract plasma. Convalescent plasma is being used to treat severe SARS-COV2 infection as it was clinically shown to be helping some patients recovering from serious illness. Current evidence of its effectiveness is based on clinical experience and its previous use during Ebola pandemic. Increased number scientific papers are being produced on this topic. As there is no effective proven treatment available for SARS-COV2 at this time, convalescent plasma is being used as drug under investigation in some countries and on ethical grounds in other countries.


Who can donate plasma?

Following are the general guidelines as a part of initial screening process of donors. Final eligibility will be determined by authorized blood banks after official screening process. Donors or patients must meet individual local, regional, or national regulations (criteria) to donate or request plasma.

  1. 1.  COVID-19 diagnosed by confirmatory laboratory diagnostic test and recovered from illness.
  2. 2.  If diagnostic test is not done and had COVID-19 like illness(symptoms), need antibody tests done and must be symptoms free.
  3. 3.  If neutralizing antibody titers are available, more than 1:160 is recommended and can consider if more than 1:80.
  4. 4.  Symptoms free for at least 2-4 weeks.
  5. 5.  Age between 18 and 65 years (or per local regulations)
  6. 6.  At least 110 Lbs (50 kgs)
  7. 7.  Must be in good health and feeling well.

What donors to expect next?

Communicate with plasma seekers where to donate (blood bank)

Keep your identity card ready

Keep the copy of test results (diagnostic or antibody) ready

Follow hospital or blood bank instructions once you arrive there You will be officially screened at the hospital or blood bank Hospitals and blood banks will determine final eligibility and safety.


Who may not be able to donate convalescent plasma?

Following are the general guidelines of screening to improve safety of patients and donors, otherwise donors or patients must meet individual local, regional, or national regulations (criteria) to donate or request plasma. Ultimate decision will be taken by blood banks (hospitals) after an official screening process.

  1. 1.  Patients with chronic medical conditions like heart failure, kidney failure etc.
  2. 2.  Patients with uncontrolled diabetes and hypertension.
  3. 3.  Patients with history of low blood pressures and dizziness.
  4. 4.  Weight less than 50 kg.
  5. 5.  Patients with history of active cancer.
  6. 6.  Patients with history of Human immunodeficiency virus infection (HIV) and Hepatitis B.
  7. 7.  Any other medical conditions, please contact your doctor or blood banks (hospitals)